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This can mean anything from administering antibiotics or antivenom to relieving pressure on the wound area to restore perfusion. The underlying cause of the necrosis in wounds must be treated before the dead tissue itself can be dealt with.
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Treatment of necrosis typically involves two distinct steps. Maintain moist wound environment to prevent dehydration and desiccation, and promote wound healing.The following precautions can help minimize the risk of developing necrotic wounds in at-risk patients and to minimize complications in patients already exhibiting symptoms: Treatments & Interventions for Necrotic Wounds Common causes of ischemia are diabetes or other metabolic disorders, or unrelieved local pressure that compresses soft tissue between a surface and underlying bony prominences (leading to the formation of pressure ulcers). Black necrotic tissue is formed when healthy tissue dies and becomes dehydrated, typically as a result of local ischemia. Necrosis can be caused by a number of external sources, including injury, infection, cancer, infarction, poisons, and inflammation. Slough is characterized as being yellow, tan, green or brown in color and may be moist, loose and stringy in appearance.įigure 1: Diabetic foot, ischemic with necrosisįigure 3: Ischemic disease, necrotic wound tissue Etiology Eschar presents as dry, thick, leathery tissue that is often tan, brown or black. There are two main types of necrotic tissue present in wounds: eschar and slough. When substantial areas of tissue become necrotic due to lack of blood supply, this is known as gangrene. For this reason, it is often necessary to remove necrotic tissue surgically, a process known as debridement. Necrotic tissue can delay wound healing, and it is often necessary for the devitalized tissue to be removed before any progress towards healing can be made. Typically, cells that die as a result of necrosis do not signal nearby phagocytes to ingest said dead cells, which leads to a build up of dead tissue and cell debris. As opposed to apoptosis, which is naturally occurring and often beneficial planned cell death, necrosis is almost always detrimental to the health of the patient and can be fatal. Necrosis is the death of cells in living tissue caused by external factors such as infection, trauma, or toxins.